Research Article
Interventions to increase personal protective behaviours to limit the spread of respiratory viruses: A rapid evidence review and meta-analysis
Purpose: Increasing personal protective behaviours is critical for stopping the spread of respiratory viruses, including SARS-CoV-2: we need evidence to inform how to achieve this. We aimed to synthesise evidence on interventions to increase six personal protective behaviours (e.g. hand hygiene, face mask use) to limit the spread of respiratory viruses.Methods: We used best practice for rapid evidence reviews. We searched Ovid MEDLINE and Scopus. Studies conducted in adults or children with active or passive comparators were included. We extracted data from published intervention descriptions on study design, intervention content, delivery mode, population, setting, mechanism(s) of action, acceptability, practicability, effectiveness, affordability, spill-over effects and equity impact. Study quality was assessed with Cochrane’s risk of bias tool. A narrative synthesis and random-effects meta-analyses were conducted.Results: We identified 39 studies conducted across 15 countries. Interventions targeted hand hygiene (n=30) and/or face mask use (n=12) and used two- or three-arm study designs with passive comparators. Interventions were typically delivered face-to-face and included a median of three behaviour change techniques. The quality of included studies was low. Interventions to increase hand hygiene (k=6) had a medium, positive effect (d=0.62, 95% CI=0.43-0.80, p<.001, I2=81.2%). Interventions targeting face mask use (k=4) had mixed results, with an imprecise pooled estimate (OR=4.14, 95% CI=1.24-13.79, p<.001, I2=89.67%). Between-study heterogeneity was high.Conclusions: We found low-quality evidence for positive effects of hand hygiene interventions, with unclear results for face mask use interventions. There was a lack of evidence for interventions targeting most behaviours of interest within this review.
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