Single nucleotide polymorphisms
Frequently called SNPs (pronounced “snips”), are the most common type of genetic variation among people. Each SNP represents a difference in a single nucleotide. For example, a SNP may replace the nucleotide cytosine (C) with the nucleotide thymine (T) in a certain stretch of DNA.SNPs occur normally throughout a person’s DNA. They occur once in every 300 nucleotides on average, which means there are roughly 10 million SNPs in the human genome. Most commonly, these variations are found in the DNA between genes. When SNPs occur within a gene or in a regulatory region near a gene, they may play a more direct role in disease by affecting the gene’s function.
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Ribonucleic acid (RNA)
A linear molecule composed of four types of smaller molecules called ribonucleotide bases: adenine (A), cytosine (C), guanine (G), and uracil (U). RNA is often compared to a copy from a reference book, or a template, because it carries the same information as its DNA template but is not used for long-term storage.
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Reward circuit
The reward pathway in the brain consisting principally of the mesolimbic dopamine system.
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Rasch analysis
An approach of mathematical modelling based on a latent trait and accomplishes stochastic (probabilistic) conjoint additivity (conjoint means measurement of persons and items on the same scale and additivity is the equal-interval property of the scale).
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Peptide
A compound containing two or more amino acids in which the carboxyl group of one acid is linked to the amino group of the other.
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