On March 12, 2020, WHO has announced COVID-19 as a pandemic due to the uncontrolled spread of SARS-Cov-2 virus, which cause severe acute respiratory tract infections. The virus penetrates the human’s body through the droplets of infected person to other person, and binds to certain receptors located on the surface of the human cells. Many challenges appeared when suggesting medicines for the treatment of Covid-19, in addition to several unanswered questions related to the vaccines’ accessibility and long-term consequences. In this paper, we would like to suggest a potential treatment for COVID-19 disease based on existing knowledge in the medical field, whether the case is mild, moderate or severe. The therapy is based on the use of carbon dioxide (CO2) either alone or as a carrier of other medication as bronchodilator, antibiotic, antiviral or anti-cytokine. The investigation shows that administration of warmed, humidified form of CO2 gas to COVID-19 patient would deactivate the viral process. Therefore, CO2 has an antimicrobial effect or can act as disinfectant.